Microfluidic technology
Next-Generation Drug Discovery Platform

The Future of
Preclinical Drug Testing

Human-Relevant 3D Tissue Models at Scale

Artificell delivers physiologically accurate organ-on-a-chip platforms that revolutionize preclinical testing. Our scaffold-free 3D tissue models provide unprecedented predictive power, reducing clinical trial failures and accelerating drug discovery.

90%
Predictive Accuracy
50%
Cost Reduction
10x
Speed Increase
The Challenge

The Clinical Translation Gap

Current preclinical testing approaches are plagued by poor clinical translation

Drug Development Attrition Flow

10,000 compounds → outcomes by scenario

The Attrition Rate

90% of all drug candidates fail during clinical development (Phase I through approval). The primary reasons are a lack of efficacy and unexpected toxicity when tested in humans.

90%
fail by Phase III

Model Accuracy Issues

<60% predictive accuracy for traditional animal models. Translation success from animal cancer studies to human trials can be as low as 8%, highlighting the limitations of current preclinical methods.

<60%
predictive accuracy

The Economic Toll

$2.6 Billion is the estimated average cost to research and develop a single new prescription drug that receives market approval, including the costs of all failed trials.

$2.6B
avg. drug development cost
The Technology

How It Works

Microfluidic engineering combined with advanced cell biology to create physiologically relevant tissue models

01

Cell Seeding

Patient-derived or iPSC cells seeded into scaffold-free microfluidic chambers

02

3D Culture

Self-organized 3D structures with controlled perfusion and physiological conditions

03

Real-Time Analysis

Integrated sensors monitoring tissue function, viability, and drug response

04

Data Output

Comprehensive datasets on efficacy, toxicity, and mechanism of action

Proprietary Advantages

Scaffold-Free Architecture

Cells organize naturally without artificial matrices, preserving native tissue structure

Physiologically Relevant

Precise control of perfusion, oxygen gradients, and mechanical forces mimics in vivo

Scalable & Automated

Automated workflows enable high-throughput screening with batch consistency

Multi-Organ Systems

Model complex drug metabolism and organ-organ interactions on single platform

Platform Applications

Fast, Simple, Versatile

From compound screening to advanced imaging—our platform adapts to your research needs

Contracting tissue in microplate well

Functional Compound Screening

Test novel compounds and get functional read-outs like beating force, beating frequency, or tissue tension in real-time with our high-throughput platform.

Compound testing workflow
96-well
Format Ready
Real-time
Data Analysis
Software Suite

Powerful Software. Effortless Analysis.

Our intuitive analysis platform transforms complex biological data into actionable insights

artificell.io/platform/analysis
Artificell software dashboard
Live Data
Export Ready
Cloud Synced

Real-Time Analytics

Monitor tissue responses with live data streaming and instant visualization

Automated Reporting

Generate publication-ready graphs and statistics with one click

Multi-Parameter Tracking

Simultaneously measure contractility, viability, and morphology

Data Management

Secure cloud storage with LIMS integration and audit trails

API Access

Integrate with your existing workflows via REST API

ML-Powered Analysis

AI-driven pattern recognition and predictive modeling

Watch Platform Demo

See our software in action with a guided 5-minute walkthrough

Technical Documentation

Download software specs, API docs, and integration guides

MANY INTEGRATES

Leadership Team

World-Class Expertise

Pioneers in bioengineering with decades of combined experience from top pharma and academic institutions

Mattias Luber

Mattias Luber

Position TBD

Background in Data Sciences

Experience TBD

Data Sciences
Dr. Arne Hofemeier

Dr. Arne Hofemeier

CEO & Co-Founder

Ph.D. Bioengineering, University Medical Center Göttingen

Ex-Regeneron Principal Scientist

Drug DiscoveryTissue EngineeringIP Strategy
Dr. Till Münker

Dr. Till Münker

Position TBD

Ph.D. Biophysics, University TBD

Experience TBD

Biophysics
Bruno Schmelz

Bruno Schmelz

Position TBD

M.S. Chemistry, University TBD

Experience TBD

Chemistry
Prof. Timo Betz

Prof. Timo Betz

Position TBD

Ph.D. Biophysics, University TBD

Experience TBD

Biophysics

Scientific Advisory Board

Guided by renowned experts from Harvard Medical School, Johns Hopkins, and leading pharma. Deep expertise in drug development, regulatory affairs, and clinical translation.

Drug Discovery
3 advisors
Regulatory Strategy
2 advisors
Clinical Translation
4 advisors
IP Strategy
2 advisors

Our Partners

Backed by top-tier biotech VCs and strategic industry partners who share our vision of transforming drug discovery through human-relevant tissue models.

Life Science Valley
Life Science Valley
University of Göttingen
University of Göttingen
SNIC Life Science Inkubator
SNIC Life Science Inkubator
Artificell's platform identified cardiotoxicity in three of our lead compounds that passed conventional screening. This early detection saved us millions in development costs and potentially years of wasted effort.
SC
Dr. Sarah Chen
VP of Preclinical Research, Leading Pharma Company
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